MALARIA: Weekly Update from Malaria Nexus

Paul-André Genest, PhD Managing Editor, Malaria Nexus   Latest News   Posted on 19 October 2012 Special issue on Malaria for Trends in Parasitology! The November issue of Trends in Parasitology was inspired by the 2012 Molecular Approaches to Malaria (MAM) conference held last February in Australia.   Posted on 19 October 2012 Repeated origin of the ability to transmit malaria in the Anopheles gambiae complex A new genetic study suggests the ability to effectively transmit human malaria would have originated multiple times in the Anopheles gambiae complex.   Posted on 19 October 2012 A novel and more effective Artemisinin Combination Therapy (ACT) A newly synthesized ACT would be twice as effective as the best drug combination currently used to treat malaria.   Posted on 18 October 2012 Discovery of an important protein for Plasmodium fertility The Armadillo Repeat Protein PF16 has recently been shown to play a significant role for Plasmodium fertility.   Posted on 16 October 2012 Launch of rapid diagnostic test (RDT) kits for malaria in Kenya At least 8 million RDTs have been procured by the Kenyan Ministry of public health for distribution in 2012 and another 11 million is planned to be supplied in 2013.   Posted on 16 October 2012 Olfactor Laboratories file for patent a new blend of compounds that can modify the biting behavior of mosquitoes The chemical technology disrupts the ability of mosquitoes to detect carbon dioxide, which is how they detect a blood meal.   Feature Articles   Posted on 18 October 2012 Autophagy in Apicomplexa: a life sustaining death mechanism? Trends in Parasitology, Volume 28, Issue 9, September 2012, Pages 358-364 Anthony P Sinai, Paul D Roepe   Posted on 18 October 2012 PI (3) P-independent and -dependent pathways function together in a vacuolar translocation sequence to target malarial proteins to the host... Molecular and Biochemical Parasitology, Volume 185, Issue 2, October 2012, Pages 106-113 Souvik Bhattacharjee, Kaye D Speicher, Robert V Stahelin, David W Speicher, Kasturi Haldar   Posted on 18 October 2012 Synthesis and antiplasmodial activity of new heteroaryl derivatives of 7-chloro-4-aminoquinoline Bioorganic and Medicinal Chemistry, Volume 20, Issue 19, 1 October 2012, Pages 5965-5979 Manolo Casagrande, Anna Barteselli, Nicoletta Basilico, Silvia Parapini, Donatella Taramelli, Anna Sparatore   Posted on 18 October 2012 Plasmodium vivax: Reverse transcriptase real-time PCR for gametocyte detection and quantitation in clinical samples Experimental Parasitology, Volume 132, Issue 3, November 2012, Pages 348-354 Nathália F Lima, Melissa S Bastos, Marcelo U Ferreira

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