MALARIA: Artesunate versus quinine in the treatment of severe falciparum malaria in African children

11 January 2011

Arjen M Dondorp, Caterina I Fanello, Ilse C E Hendriksen, et al
Severe malaria is a major cause of childhood death and often the main reason for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established treatment of choice, although evidence from Asia suggests that artesunate is associated with a lower mortality. We compared parenteral treatment with either artesunate or quinine in African children with severe malaria.
http://www.malarianexus.com/articles/read/116/artesunate-versus-quinine-in-the-treatment-of-severe-falciparum-malaria-in-african-children-aquamat-an-open-label-randomised-trial/