Monday 10 December 2012

MALARIA: Weekly Update from Malaria Nexus

 
Study identifies a platelet protein responsible for platelet-mediated killing of Plasmodium falciparum
Posted on 07 December 2012
Study identifies a platelet protein responsible for platelet-mediated killing of Plasmodium falciparum
A team of researchers based in Australia recently described the role of the protein platelet factor 4 in mediating the platelet-mediated killing of Plasmodium falciparum.
 
Treatment with anti-HIV drugs lowers the risk of malaria infection
Posted on 07 December 2012
Treatment with anti-HIV drugs lowers the risk of malaria infection
A clinical trial recently reported that treatment of HIV-infected children with antiretroviral drugs reduced the recurrence of malaria infection.
 
A protein involved in iron metabolism regulates both the innate and adaptive immune responses to malaria infection
Posted on 06 December 2012
A protein involved in iron metabolism regulates both the innate and adaptive immune responses to malaria infection
An article recently published in Cell Host & Microbe describes the implication of the iron-sequestering protein Lipocalin 2 in controlling the immune responses to malaria.
 
Special IJPDDR issue covers the 2012 Keystone Symposium on Drug Discovery for Protozoan Parasites!
Posted on 06 December 2012
Special IJPDDR issue covers the 2012 Keystone Symposium on Drug Discovery for Protozoan Parasites!
The International Journal for Parasitology: Drugs and Drug Resistance (IJPDDR) released a special issue covering the recently held Keystone Symposium on Drug Discovery for Protozoan Parasites.
 
Feature Articles
 
Posted on 06 December 2012
Lipocalin 2 Bolsters Innate and Adaptive Immune Responses to Blood-Stage Malaria Infection by Reinforcing Host Iron Metabolism
Cell Host & Microbe, Volume 12, Issue 5, 15 November 2012, Pages 705-716
Hong Zhao, Aki Konishi, Yukiko Fujita, Masanori Yagi, Keiichi Ohata, Taiki Aoshi, Sawako Itagaki, Shintaro Sato, Hirotaka Narita, Noha H. Abdelgelil, Megumi Inoue, Richard Culleton, Osamu Kaneko, Atsushi Nakagawa, Toshihiro Horii, et al.
 
Posted on 06 December 2012
Wherever I may roam: Protein and membrane trafficking in P. falciparum-infected red blood cells
Molecular and Biochemical Parasitology, Volume 186, Issue 2, December 2012, Pages 95-116
Marcel Deponte, Heinrich C. Hoppe, Marcus C.S. Lee, Alexander G. Maier, Dave Richard, Melanie Rug, Tobias Spielmann, Jude M. Przyborski
 
Posted on 06 December 2012
Chemotherapeutics challenges in developing effective treatments for the endemic malarias
International Journal for Parasitology: Drugs and Drug Resistance, Volume 2, December 2012, Pages 256-261
J. Kevin Baird
 
Posted on 06 December 2012
Artemisinin resistance in Plasmodium falciparum: A process linked to dormancy?
International Journal for Parasitology: Drugs and Drug Resistance, Volume 2, December 2012, Pages 249-255
Qin Cheng, Dennis E. Kyle, Michelle L. Gatton

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