MALARIA: Weekly Update from Malaria Nexus

Posted on 07 December 2012 Study identifies a platelet protein responsible for platelet-mediated killing of Plasmodium falciparum A team of researchers based in Australia recently described the role of the protein platelet factor 4 in mediating the platelet-mediated killing of Plasmodium falciparum.   Posted on 07 December 2012 Treatment with anti-HIV drugs lowers the risk of malaria infection A clinical trial recently reported that treatment of HIV-infected children with antiretroviral drugs reduced the recurrence of malaria infection.   Posted on 06 December 2012 A protein involved in iron metabolism regulates both the innate and adaptive immune responses to malaria infection An article recently published in Cell Host & Microbe describes the implication of the iron-sequestering protein Lipocalin 2 in controlling the immune responses to malaria.   Posted on 06 December 2012 Special IJPDDR issue covers the 2012 Keystone Symposium on Drug Discovery for Protozoan Parasites! The International Journal for Parasitology: Drugs and Drug Resistance (IJPDDR) released a special issue covering the recently held Keystone Symposium on Drug Discovery for Protozoan Parasites.   Feature Articles   Posted on 06 December 2012 Lipocalin 2 Bolsters Innate and Adaptive Immune Responses to Blood-Stage Malaria Infection by Reinforcing Host Iron Metabolism Cell Host & Microbe, Volume 12, Issue 5, 15 November 2012, Pages 705-716 Hong Zhao, Aki Konishi, Yukiko Fujita, Masanori Yagi, Keiichi Ohata, Taiki Aoshi, Sawako Itagaki, Shintaro Sato, Hirotaka Narita, Noha H. Abdelgelil, Megumi Inoue, Richard Culleton, Osamu Kaneko, Atsushi Nakagawa, Toshihiro Horii, et al.   Posted on 06 December 2012 Wherever I may roam: Protein and membrane trafficking in P. falciparum-infected red blood cells Molecular and Biochemical Parasitology, Volume 186, Issue 2, December 2012, Pages 95-116 Marcel Deponte, Heinrich C. Hoppe, Marcus C.S. Lee, Alexander G. Maier, Dave Richard, Melanie Rug, Tobias Spielmann, Jude M. Przyborski   Posted on 06 December 2012 Chemotherapeutics challenges in developing effective treatments for the endemic malarias International Journal for Parasitology: Drugs and Drug Resistance, Volume 2, December 2012, Pages 256-261 J. Kevin Baird   Posted on 06 December 2012 Artemisinin resistance in Plasmodium falciparum: A process linked to dormancy? International Journal for Parasitology: Drugs and Drug Resistance, Volume 2, December 2012, Pages 249-255 Qin Cheng, Dennis E. Kyle, Michelle L. Gatton

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