MALARIA: Weekly Update from Malaria Nexus March 22

Latest News   Posted on 22 March 2013 Waning protection of the RTS,S malaria candidate vaccine over time A study recently published in The New England Journal of Medicine reports a reduced protection conferred by the RTS,S malaria candidate vaccine over time.   Posted on 22 March 2013 A newly discovered class of anti-malarial compounds targets multiple stages of the malaria parasite's life cycle A study recently published in Science Translational Medicine describes novel endochin derivatives that target the gametocytes as well as the liver, blood and vector stages of Plasmodium spp.   Posted on 22 March 2013 The abstract deadline for the conference “Advances in Plasmodium vivax Malaria Research” is fast approaching! The conference “Advances in Plasmodium vivax Malaria Research” will be held in Barcelona on May 28-29, 2013. The abstract deadline for the conference is April 5, 2013.   Feature Articles   Posted on 22 March 2013 Substrate specificity studies of the cysteine peptidases falcipain-2 and falcipain-3 from Plasmodium falciparum and demonstration of their... Molecular and Biochemical Parasitology, Volume 187, Issue 2, February 2013, Pages 111-116 Simone S. Cotrin, Iuri E. Gouvêa, Pollyana M.S. Melo, Piero Bagnaresi, Diego M. Assis, Mariana S. Araújo, Maria Aparecida Juliano, Marcos L. Gazarini, Philip J. Rosenthal, Luiz Juliano, Adriana K. Carmona   Posted on 22 March 2013 Detection of copy number variation and single nucleotide polymorphisms in genes involved in drug resistance and other phenotypic traits in... Acta Tropica, Volume 125, Issue 3, March 2013, Pages 269-275 Mpungu Steven Kiwuwa, Justus Byarugaba, Mats Wahlgren, Fred Kironde   Posted on 22 March 2013 Discovery of non-peptide inhibitors of Plasmepsin II by structure-based virtual screening Bioorganic & Medicinal Chemistry Letters, Volume 23, Issue 7, 1 April 2013, Pages 2078-2082 Yuwei Song, Huangtao Jin, Xiaofeng Liu, Lili Zhu, Jin Huang, Honglin Li   Posted on 22 March 2013 Biochemical properties, expression profiles, and tissue localization of orthologous acetylcholinesterase-2 in the mosquito, Anopheles gambiae Insect Biochemistry and Molecular Biology, Volume 43, Issue 3, March 2013, Pages 260-271 Picheng Zhao, Yang Wang, Haobo Jiang

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