Sunday, 3 April 2011

MALARIA: vaccinating the mosquito

William Brieger

O'Neill's approach vaccinates mosquitoes instead of patients. In his lab, under a microscope, workers inject the bacterium Wolbachia pipientis, which is harmless to humans and common among insects, into eggs of Aedes aegypti mosquitoes, a major carrier of the dengue microbe.
O'Neill has found that Wolbachia makes A. aegypti resistant to-and unable to transmit-the disease.
What is more, all progeny inherit immunity.

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