Friday 17 May 2013

MALARIA: Three new articles published in Malaria Journal


For articles which have only just been published, you will see a 'provisional PDF' corresponding to the accepted manuscript. A fully formatted PDF and full text (HTML) version will be made available soon.
Commentary      Fulani show decreased susceptibility to Plasmodium falciparum infection versus Mossi: data from a community-wide screening and treatment of asymptomatic carriers in Burkina Faso Tiono AB, Sirima SB, Hamed K 
Malaria Journal 2013, 12:163 (16 May 2013)
[Abstract] [Provisional PDF]

Background

The Fulani ethnic group is known to have a lower susceptibility to Plasmodium falciparum infection than the Mossi.

Methods

This commentary describes data from a recent cluster-randomized trial of community-wide screening and treatment of asymptomatic carriers of P. falciparum in 18 villages in Sapone, Burkina Faso.

Results

The Fulani groups had a lower proportion of asymptomatic carriers at any occasion, a lower density of asexual forms and gametocytes of P. falciparum at baseline, and, in children under five years of age, lower rates of symptomatic malaria episodes per person-year than the Mossi.
Discussion and conclusion: These data confirm previously reported differences in P. falciparum susceptibility between Fulani and Mossi.
 
Research      Evaluation of the 2011 long-lasting, insecticide-treated net distribution for universal coverage in Togo Stevens ER, Aldridge A, Degbey Y, Pignandi A, Dorkenoo MA, Hugelen-Padin J 
Malaria Journal 2013, 12:162 (16 May 2013)
[Abstract] [Provisional PDF]

Background

Malaria remains a substantial public health problem in Togo. An integrated child health campaign was conducted in Togo in October 2011. This campaign included a component of free distribution of 2,799,800 long-lasting, insecticide-treated nets (LLINs) to households throughout Togo. This distribution marked the first effort in Togo at universal LLIN coverage and was not targeted specifically to children under five years and pregnant women, but to all household members. This study reports the results of the LLIN distribution campaign in terms of bed net possession and utilization.

Methods

A representative household survey was implemented during the rainy season nine months after the LLIN distribution component of the campaign. Some 6,015 households selected through two stages of probability proportion to size stratified random sampling were interviewed using a brief questionnaire that included a demographic section with questions on the number of household members and sleeping spaces, and a campaign participation section with questions used to evaluate non-LLIN aspects of the campaign. A net roster listed all nets and their characteristics, and a household roster listed all members and visitors with information about bed net use. The questions addressed different aspects of bed net and LLIN possession and utilization. Crude weighted frequencies, percentages, and t- tests of association were calculated using the Stata 12.0 Survey features.

Results

Possession of at least one bed net and/ or LLIN increased from 41.3% to 96.7% (P <0 .001="" 68.3="" 77.5="" 79.3="" 93.3="" among="" and="" at="" campaign="" children="" div="" five.="" for="" general="" household="" least="" llin="" of="" one="" population="" possession="" pregnant="" report="" the="" under="" use="" was="" women="">

Conclusions

Due to the gap in LLIN possession and use and the significant number of individuals reporting a lack of nets as a reason for non-use, additional national LLIN distribution campaigns with a stronger educational component need to be implemented in order increase the use of available LLINs and to reach and maintain universal coverage of LLINs in Togo. The LLIN distribution campaign focusing on universal coverage of the general population in Togo was more successful at increasing LLIN possession and use of children under five years and pregnant women than other campaigns focusing only on these target groups.
 
Research      Providing open access data online to advance malaria research and control Moyes CL, Temperley WH, Henry AJ, Burgert CR, Hay SI 
Malaria Journal 2013, 12:161 (16 May 2013)
[Abstract] [Provisional PDF]

Background

To advance research on malaria, the outputs from existing studies and the data that fed into them need to be made freely available. This will ensure new studies can build on the work that has gone before. These data and results also need to be made available to groups who are developing public health policies based on up-to-date evidence. The Malaria Atlas Project (MAP) has collated and geopositioned over 50,000 parasite prevalence and vector occurrence survey records contributed by over 3,000 sources including research groups, government agencies and non-governmental organizations worldwide. This paper describes the results of a project set up to release data gathered, used and generated by MAP.

Methods

Requests for permission to release data online were sent to 236 groups who had contributed unpublished prevalence (parasite rate) surveys. An online explorer tool was developed so that users can visualize the spatial distribution of the vector and parasite survey data before downloading it. In addition, a consultation group was convened to provide advice on the mode and format of release for data generated by MAP's modelling work. New software was developed to produce a suite of publication-quality map images for download from the internet for use in external publications.

Conclusion

More than 40,000 survey records can now be visualized on a set of dynamic maps and downloaded from the MAP website on a free and unrestricted basis. As new data are added and new permissions to release existing data come in, the volume of data available for download will increase. The modelled data output from MAP's own analyses are also available online in a range of formats, including image files and GIS surface data, for use in advocacy, education, further research and to help parameterize or validate other mathematical models.

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