Friday, 21 June 2013

MALARIA: Targeting Asymptomatic Malaria Infections

Targeting Asymptomatic Malaria Infections: Active Surveillance in Control and Elimination

  • Hugh J. W. Sturrock mail,
  • Michelle S. Hsiang,
  • Justin M. Cohen,
  • David L. Smith,
  • Bryan Greenhouse,
  • Teun Bousema,
  • Roly D. Gosling
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Summary Points

  • Active case detection (ACD) is a recommended intervention in low malaria transmission settings, yet evidence for its effectiveness is sparse.
  • The potential of ACD to impact transmission is hampered by the ability of current field diagnostics to detect very low density infections and continued importation of parasites, as well as the operational challenges of achieving high coverage.
  • The type of ACD employed should be guided by transmission setting and an understanding of risk factors.
  • Standardized monitoring and evaluation of ACD strategies should be an integral component of ACD campaigns.
  • In light of the current sensitivity of field diagnostic tests, targeted mass drug administration should be evaluated as an alternative or addition to ACD in low transmission settings.

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